… a rapid-acting antidepressant in patients with MDD and active … , change in CGI-SS-r from
baseline to 24 hours after the first … 90, indicating the patient was normal/questionably suicidal. …

… This study compared the efficacy and safety of switching patients with treatment-resistant …
randomized trial of an N-methyl-d-aspartate antagonist in treatment-resistant major depression. …

… patients with MDD unresponsive to standard antidepressants… the first antidepressant treatment.
Moreover, the response to … change from baseline were observed on day 14 for patients in …

… severity of the symptoms unlike traditional antidepressants … In a double-blind randomized
trial,27 the addition of SAMe to … patients with major depressive disorder. In a small, open-label, …

… (SSRIs) are more effective in patients with resistant OCD than severe major depressive
disorder… Y-BOCS total score change from baseline to the end of the trial between the two groups. …

… , this study is the first double‐blind, randomized, and placebo‐… restored to the normal levels
by the antidepressant therapy. … a decrease in HDRS after switching from milnacipran to CLS (…

… change from baseline in the visual analogue scale for pain (… or caused an inability to perform
normal activities of daily living … antidepressants is 2–4 weeks, which contributes to an early …

… ) total score change from baseline to the end of the study. Safety … Currently, most approved
antidepressants for MDD primarily … as first-line treatment for most patients with MDD. The …

… improved after shifting the time of taking the medicine to the early evening … antidepressant
effects in conjunction with conventional antidepressant drugs in patients with major depression…

… , met criteria for major depressive disorder (MDD) by the … to at least two adequate
antidepressant trials of different … in this study, this is the largest randomized study that compare …